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The Multiple Mitotic Roles of the ASPM Orthologous Proteins: Insight into the Etiology of ASPM-Dependent Microcephaly

The Drosophila abnormal spindle (asp) gene was discovered about 40 years ago and shown to be required for both mitotic and meiotic cell division. Subsequent studies showed that asp is highly conserved and that mutations in its human ortholog ASPM (Abnormal Spindle-like Microcephaly-associated; or MC...

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Detalles Bibliográficos
Autores principales: Razuvaeva, Alyona V., Graziadio, Lucia, Palumbo, Valeria, Pavlova, Gera A., Popova, Julia V., Pindyurin, Alexey V., Bonaccorsi, Silvia, Somma, Maria Patrizia, Gatti, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047693/
https://www.ncbi.nlm.nih.gov/pubmed/36980263
http://dx.doi.org/10.3390/cells12060922

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