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Effect of HPSE and HPSE2 SNPs on the Risk of Developing Primary Paraskeletal Multiple Myeloma
Multiple myeloma (MM) is a plasma cell malignancy that is accompanied by hypercalcemia, renal failure, anemia, and lytic bone lesions. Heparanase (HPSE) plays an important role in supporting and promoting myeloma progression, maintenance of plasma cell stemness, and resistance to therapy. Previous s...
Autores principales: | Ostrovsky, Olga, Beider, Katia, Magen, Hila, Leiba, Merav, Sanderson, Ralph D., Vlodavsky, Israel, Nagler, Arnon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047783/ https://www.ncbi.nlm.nih.gov/pubmed/36980254 http://dx.doi.org/10.3390/cells12060913 |
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