Autophagy Function and Benefits of Autophagy Induction in Models of Spinocerebellar Ataxia Type 3

Background: Spinocerebellar ataxia 3 (SCA3, also known as Machado Joseph disease) is a fatal neurodegenerative disease caused by the expansion of the trinucleotide repeat region within the ATXN3/MJD gene. The presence of this genetic expansion results in an ataxin-3 protein containing a polyglutamin...

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Detalles Bibliográficos
Autores principales: Watchon, Maxinne, Luu, Luan, Plenderleith, Stuart K., Yuan, Kristy C., Laird, Angela S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047838/
https://www.ncbi.nlm.nih.gov/pubmed/36980234
http://dx.doi.org/10.3390/cells12060893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047838/
https://www.ncbi.nlm.nih.gov/pubmed/36980234
http://dx.doi.org/10.3390/cells12060893

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