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Autophagy Function and Benefits of Autophagy Induction in Models of Spinocerebellar Ataxia Type 3
Background: Spinocerebellar ataxia 3 (SCA3, also known as Machado Joseph disease) is a fatal neurodegenerative disease caused by the expansion of the trinucleotide repeat region within the ATXN3/MJD gene. The presence of this genetic expansion results in an ataxin-3 protein containing a polyglutamin...
Autores principales: | Watchon, Maxinne, Luu, Luan, Plenderleith, Stuart K., Yuan, Kristy C., Laird, Angela S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047838/ https://www.ncbi.nlm.nih.gov/pubmed/36980234 http://dx.doi.org/10.3390/cells12060893 |
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