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JNK Activation Correlates with Cognitive Impairment and Alteration of the Post-Synaptic Element in the 5xFAD AD Mouse Model

The c-Jun N-terminal kinases (JNKs) are a family of proteins that, once activated by stress stimuli, can alter neuronal functions and survival. The JNK cascade plays a crucial role in the post-synaptic neuronal compartment by altering its structural organization and leading, at worst, to an overall...

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Detalles Bibliográficos
Autores principales: Priori, Erica Cecilia, Musi, Clara Alice, Giani, Arianna, Colnaghi, Luca, Milic, Ivana, Devitt, Andrew, Borsello, Tiziana, Repici, Mariaelena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047857/
https://www.ncbi.nlm.nih.gov/pubmed/36980245
http://dx.doi.org/10.3390/cells12060904

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