Cargando…
JNK Activation Correlates with Cognitive Impairment and Alteration of the Post-Synaptic Element in the 5xFAD AD Mouse Model
The c-Jun N-terminal kinases (JNKs) are a family of proteins that, once activated by stress stimuli, can alter neuronal functions and survival. The JNK cascade plays a crucial role in the post-synaptic neuronal compartment by altering its structural organization and leading, at worst, to an overall...
Autores principales: | Priori, Erica Cecilia, Musi, Clara Alice, Giani, Arianna, Colnaghi, Luca, Milic, Ivana, Devitt, Andrew, Borsello, Tiziana, Repici, Mariaelena |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047857/ https://www.ncbi.nlm.nih.gov/pubmed/36980245 http://dx.doi.org/10.3390/cells12060904 |
Ejemplares similares
-
Colocalization and Interaction Study of Neuronal JNK3, JIP1, and β-Arrestin2 Together with PSD95
por: Musi, Clara Alice, et al.
Publicado: (2022) -
Synaptic alterations as a common phase in neurological and neurodevelopmental diseases: JNK is a key mediator in synaptic changes
por: Musi, Clara Alice, et al.
Publicado: (2022) -
Effect of 3D Synthetic Microscaffold Nichoid on the Morphology of Cultured Hippocampal Neurons and Astrocytes
por: Musi, Clara Alice, et al.
Publicado: (2022) -
Aromatase Expression in the Hippocampus of AD Patients and 5xFAD Mice
por: Prange-Kiel, Janine, et al.
Publicado: (2016) -
JNK3 as Therapeutic Target and Biomarker in Neurodegenerative and Neurodevelopmental Brain Diseases
por: Musi, Clara Alice, et al.
Publicado: (2020)