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Risk-Stratified Breast Cancer Screening Incorporating a Polygenic Risk Score: A Survey of UK General Practitioners’ Knowledge and Attitudes

A polygenic risk score (PRS) quantifies the aggregated effects of common genetic variants in an individual. A ‘personalised breast cancer risk assessment’ combines PRS with other genetic and nongenetic risk factors to offer risk-stratified screening and interventions. Large-scale studies are evaluat...

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Detalles Bibliográficos
Autores principales: Ayoub, Aya, Lapointe, Julie, Nabi, Hermann, Pashayan, Nora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048009/
https://www.ncbi.nlm.nih.gov/pubmed/36981003
http://dx.doi.org/10.3390/genes14030732

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