Zeb2 DNA-Binding Sites in Neuroprogenitor Cells Reveal Autoregulation and Affirm Neurodevelopmental Defects, Including in Mowat-Wilson Syndrome

Functional perturbation and action mechanism studies have shown that the transcription factor Zeb2 controls cell fate decisions, differentiation, and/or maturation in multiple cell lineages in embryos and after birth. In cultured embryonic stem cells (ESCs), Zeb2’s mRNA/protein upregulation is neces...

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Detalles Bibliográficos
Autores principales: Birkhoff, Judith C., Korporaal, Anne L., Brouwer, Rutger W. W., Nowosad, Karol, Milazzo, Claudia, Mouratidou, Lidia, van den Hout, Mirjam C. G. N., van IJcken, Wilfred F. J., Huylebroeck, Danny, Conidi, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048071/
https://www.ncbi.nlm.nih.gov/pubmed/36980900
http://dx.doi.org/10.3390/genes14030629

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