Systemic Retinoids for Generalized Verrucosis Due to Congenital Immunodeficiency: Case Reports and Review of the Literature

Generalized verrucosis (GV) is a group of immunodeficiency disorders accompanied by widespread human papillomavirus infection. We revisit two cases of GV due to congenital interleukin-7 deficiency successfully treated with systemic retinoids. We also present a review of the literature on the use of...

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Autores principales: Kosumi, Hideyuki, Natsuga, Ken, Yanagi, Teruki, Ujiie, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048204/
https://www.ncbi.nlm.nih.gov/pubmed/36981039
http://dx.doi.org/10.3390/genes14030769
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author Kosumi, Hideyuki
Natsuga, Ken
Yanagi, Teruki
Ujiie, Hideyuki
author_facet Kosumi, Hideyuki
Natsuga, Ken
Yanagi, Teruki
Ujiie, Hideyuki
author_sort Kosumi, Hideyuki
collection PubMed
description Generalized verrucosis (GV) is a group of immunodeficiency disorders accompanied by widespread human papillomavirus infection. We revisit two cases of GV due to congenital interleukin-7 deficiency successfully treated with systemic retinoids. We also present a review of the literature on the use of systemic retinoids to treat GV. Our review suggests that systemic retinoids are a safe and effective option for managing recalcitrant wart lesions in cases of GV.
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spelling pubmed-100482042023-03-29 Systemic Retinoids for Generalized Verrucosis Due to Congenital Immunodeficiency: Case Reports and Review of the Literature Kosumi, Hideyuki Natsuga, Ken Yanagi, Teruki Ujiie, Hideyuki Genes (Basel) Opinion Generalized verrucosis (GV) is a group of immunodeficiency disorders accompanied by widespread human papillomavirus infection. We revisit two cases of GV due to congenital interleukin-7 deficiency successfully treated with systemic retinoids. We also present a review of the literature on the use of systemic retinoids to treat GV. Our review suggests that systemic retinoids are a safe and effective option for managing recalcitrant wart lesions in cases of GV. MDPI 2023-03-22 /pmc/articles/PMC10048204/ /pubmed/36981039 http://dx.doi.org/10.3390/genes14030769 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Opinion
Kosumi, Hideyuki
Natsuga, Ken
Yanagi, Teruki
Ujiie, Hideyuki
Systemic Retinoids for Generalized Verrucosis Due to Congenital Immunodeficiency: Case Reports and Review of the Literature
title Systemic Retinoids for Generalized Verrucosis Due to Congenital Immunodeficiency: Case Reports and Review of the Literature
title_full Systemic Retinoids for Generalized Verrucosis Due to Congenital Immunodeficiency: Case Reports and Review of the Literature
title_fullStr Systemic Retinoids for Generalized Verrucosis Due to Congenital Immunodeficiency: Case Reports and Review of the Literature
title_full_unstemmed Systemic Retinoids for Generalized Verrucosis Due to Congenital Immunodeficiency: Case Reports and Review of the Literature
title_short Systemic Retinoids for Generalized Verrucosis Due to Congenital Immunodeficiency: Case Reports and Review of the Literature
title_sort systemic retinoids for generalized verrucosis due to congenital immunodeficiency: case reports and review of the literature
topic Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048204/
https://www.ncbi.nlm.nih.gov/pubmed/36981039
http://dx.doi.org/10.3390/genes14030769
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