Cargando…

The Developmental Origins of Cancer: A Review of the Genes Expressed in Embryonic Cells with Implications for Tumorigenesis

Tumorigenesis, which involves the uncontrolled proliferation and differentiation of cells, has been observed to imitate a variety of pathways vital to embryonic development, motivating cancer researchers to explore the genetic origins of these pathways. The pluripotency gene regulatory network is an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Balachandran, Savitha, Narendran, Aru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048275/ https://www.ncbi.nlm.nih.gov/pubmed/36980876 http://dx.doi.org/10.3390/genes14030604

Ejemplares similares

Mesenchymal stem/stromal cells: Developmental origin, tumorigenesis and translational cancer therapeutics
por: Li, Chenghai, et al.
Publicado: (2020)

Identification of Altered Primary Immunodeficiency-Associated Genes and Their Implications in Pediatric Cancers
por: Standing, Shaelene, et al.
Publicado: (2022)

Survivin as a Preferential Target for Cancer Therapy
por: Mobahat, Mahsa, et al.
Publicado: (2014)

Evaluation of COVID-19 vaccine response in patients with cancer: An interim analysis
por: Tran, Son, et al.
Publicado: (2021)

Human embryonic stem cells as an in vitro model for studying developmental origins of type 2 diabetes
por: Chen, Andy Chun-Hang, et al.
Publicado: (2020)

A Developmental Perspective on Paragangliar Tumorigenesis
por: Lotti, Lavinia Vittoria, et al.
Publicado: (2019)

Neoantigen Cancer Vaccines: Generation, Optimization, and Therapeutic Targeting Strategies
por: Reynolds, Carson R., et al.
Publicado: (2022)

Embryonic origins of human vascular smooth muscle cells: implications for in vitro modeling and clinical application
por: Sinha, Sanjay, et al.
Publicado: (2014)

Cell Reprogramming in Tumorigenesis and Its Therapeutic Implications for Breast Cancer
por: Chu, Pei-Yi, et al.
Publicado: (2019)

A topographic atlas defines developmental origins of cell heterogeneity in the human embryonic lung
por: Sountoulidis, Alexandros, et al.
Publicado: (2023)

Developmental origins of non-communicable disease: Implications for research and public health
por: Barouki, Robert, et al.
Publicado: (2012)

Gene Expression and Regulation in Adrenocortical Tumorigenesis
por: Fonseca, Annabelle L., et al.
Publicado: (2012)

Pituitary Tumorigenesis—Implications for Management
por: Vamvoukaki, Rodanthi, et al.
Publicado: (2023)

Prostate cancer stem cells: deciphering the origins and pathways involved in prostate tumorigenesis and aggression
por: Rybak, Adrian P., et al.
Publicado: (2014)

Loss of Function of E-Cadherin in Embryonic Stem Cells and the Relevance to Models of Tumorigenesis
por: Mohamet, Lisa, et al.
Publicado: (2011)

The hepatocyte growth factor/mesenchymal epithelial transition factor axis in high-risk pediatric solid tumors and the anti-tumor activity of targeted therapeutic agents
por: Grundy, Megan, et al.
Publicado: (2022)

Developmental origin of chronic diseases: toxicological implication
por: Bezek, Štefan, et al.
Publicado: (2008)

Olfactomedin-like 3: possible functions in embryonic development and tumorigenesis
por: Jin, Ying, et al.
Publicado: (2019)

The Expanding Universe of Prion Diseases
por: Watts, Joel C, et al.
Publicado: (2006)

Aberrant expression of embryonic mesendoderm factor MESP1 promotes tumorigenesis
por: Tandon, Neha, et al.
Publicado: (2019)

Ectopic expression of PTTG1/securin promotes tumorigenesis in human embryonic kidney cells
por: Hamid, Tariq, et al.
Publicado: (2005)

Mechanisms of TP53 Pathway Inactivation in Embryonic and Somatic Cells—Relevance for Understanding (Germ Cell) Tumorigenesis
por: Timmerman, Dennis M., et al.
Publicado: (2021)

Embryonic stem cells: An alternative approach to developmental toxicity testing
por: Tandon, S., et al.
Publicado: (2012)

Developmental transcriptomics throughout the embryonic developmental process of Rhipicephalus turanicus reveals stage-specific gene expression profiles
por: Ruiling, Zhang, et al.
Publicado: (2022)

Developmental origins of adult diseases
por: Mo, Jiaying, et al.
Publicado: (2022)

Activation of the IGF Axis in Thyroid Cancer: Implications for Tumorigenesis and Treatment
por: Manzella, Livia, et al.
Publicado: (2019)

Implications of HIF-1α in the tumorigenesis and progression of pancreatic cancer
por: Jin, Xiao, et al.
Publicado: (2020)

Nuclear PTEN’s Functions in Suppressing Tumorigenesis: Implications for Rare Cancers
por: Langdon, Casey G.
Publicado: (2023)

Targeted inhibition of MEK1 by cobimetinib leads to differentiation and apoptosis in neuroblastoma cells
por: Singh, Anjali, et al.
Publicado: (2015)

Embryonic Kidney Development, Stem Cells and the Origin of Wilms Tumor
por: Li, Hao, et al.
Publicado: (2021)

Reactivation of a developmentally silenced embryonic globin gene
por: King, Andrew J., et al.
Publicado: (2021)

Comprehensive Review of Uterine Fibroids: Developmental Origin, Pathogenesis, and Treatment
por: Yang, Qiwei, et al.
Publicado: (2021)

The Small-Molecule E26-Transformation-Specific Inhibitor TK216 Attenuates the Oncogenic Properties of Pediatric Leukemia
por: Sharma, Ritul, et al.
Publicado: (2023)

ETMR-08. INTERNATIONAL CONSENSUS PROTOCOL FOR EMBRYONAL TUMOR WITH MULTILAYER ROSETTES
por: Hanson, Derek, et al.
Publicado: (2020)

The Implications of the Developmental Origins of Health and Disease on Public Health Policy and Health Promotion in South Africa
por: Reddy, Sasiragha Priscilla, et al.
Publicado: (2016)

Cell Signaling Coordinates Global PRC2 Recruitment and Developmental Gene Expression in Murine Embryonic Stem Cells
por: Aljazi, Mohammad B., et al.
Publicado: (2020)

Inhibitor of DNA Binding 2 (ID2) Regulates the Expression of Developmental Genes and Tumorigenesis in Ewing Sarcoma
por: Koppenhafer, Stacia L., et al.
Publicado: (2022)

Developmental origins of adult diseases
por: Mathew, Vivek, et al.
Publicado: (2012)

Embryonic stem cells shed new light on the developmental roles of p53
por: Shin, Min Hwa, et al.
Publicado: (2013)

Chromatin and Cancer: Implications of Disrupted Chromatin Organization in Tumorigenesis and Its Diversification
por: Sehgal, Poonam, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8fg0deihjnvfsv9934o4ke55k9