PARK2 Microdeletion or Duplications Have Been Implicated in Different Neurological Disorders Including Early Onset Parkinson Disease

The PARK2 gene is located on 6q26, encodes ubiquitin-E3- ligase, and is a transcriptional repressor of p53. It contains 12 exons. PARK2 copy number variants has been reported in various types of neurodevelopmental disorders, namely schizophrenia, Parkinson’s disease (PD), autism spectrum disorder (A...

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Detalles Bibliográficos
Autores principales: Ahmad, Ausaf, Nkosi, Dingani, Iqbal, Mohammed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048322/
https://www.ncbi.nlm.nih.gov/pubmed/36980871
http://dx.doi.org/10.3390/genes14030600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048322/
https://www.ncbi.nlm.nih.gov/pubmed/36980871
http://dx.doi.org/10.3390/genes14030600

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