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Koala Genome Survey: An Open Data Resource to Improve Conservation Planning

Genome sequencing is a powerful tool that can inform the management of threatened species. Koalas (Phascolarctos cinereus) are a globally recognized species that captured the hearts and minds of the world during the 2019/2020 Australian megafires. In 2022, koalas were listed as ‘Endangered’ in Queen...

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Autores principales: Hogg, Carolyn J., Silver, Luke, McLennan, Elspeth A., Belov, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048327/
https://www.ncbi.nlm.nih.gov/pubmed/36980819
http://dx.doi.org/10.3390/genes14030546
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author Hogg, Carolyn J.
Silver, Luke
McLennan, Elspeth A.
Belov, Katherine
author_facet Hogg, Carolyn J.
Silver, Luke
McLennan, Elspeth A.
Belov, Katherine
author_sort Hogg, Carolyn J.
collection PubMed
description Genome sequencing is a powerful tool that can inform the management of threatened species. Koalas (Phascolarctos cinereus) are a globally recognized species that captured the hearts and minds of the world during the 2019/2020 Australian megafires. In 2022, koalas were listed as ‘Endangered’ in Queensland, New South Wales, and the Australian Capital Territory. Populations have declined because of various threats such as land clearing, habitat fragmentation, and disease, all of which are exacerbated by climate change. Here, we present the Koala Genome Survey, an open data resource that was developed after the Australian megafires. A systematic review conducted in 2020 demonstrated that our understanding of genomic diversity within koala populations was scant, with only a handful of SNP studies conducted. Interrogating data showed that only 6 of 49 New South Wales areas of regional koala significance had meaningful genome-wide data, with only 7 locations in Queensland with SNP data and 4 locations in Victoria. In 2021, we launched the Koala Genome Survey to generate resequenced genomes across the Australian east coast. We have publicly released 430 koala genomes (average coverage: 32.25X, range: 11.3–66.8X) on the Amazon Web Services Open Data platform to accelerate research that can inform current and future conservation planning.
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spelling pubmed-100483272023-03-29 Koala Genome Survey: An Open Data Resource to Improve Conservation Planning Hogg, Carolyn J. Silver, Luke McLennan, Elspeth A. Belov, Katherine Genes (Basel) Communication Genome sequencing is a powerful tool that can inform the management of threatened species. Koalas (Phascolarctos cinereus) are a globally recognized species that captured the hearts and minds of the world during the 2019/2020 Australian megafires. In 2022, koalas were listed as ‘Endangered’ in Queensland, New South Wales, and the Australian Capital Territory. Populations have declined because of various threats such as land clearing, habitat fragmentation, and disease, all of which are exacerbated by climate change. Here, we present the Koala Genome Survey, an open data resource that was developed after the Australian megafires. A systematic review conducted in 2020 demonstrated that our understanding of genomic diversity within koala populations was scant, with only a handful of SNP studies conducted. Interrogating data showed that only 6 of 49 New South Wales areas of regional koala significance had meaningful genome-wide data, with only 7 locations in Queensland with SNP data and 4 locations in Victoria. In 2021, we launched the Koala Genome Survey to generate resequenced genomes across the Australian east coast. We have publicly released 430 koala genomes (average coverage: 32.25X, range: 11.3–66.8X) on the Amazon Web Services Open Data platform to accelerate research that can inform current and future conservation planning. MDPI 2023-02-22 /pmc/articles/PMC10048327/ /pubmed/36980819 http://dx.doi.org/10.3390/genes14030546 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Hogg, Carolyn J.
Silver, Luke
McLennan, Elspeth A.
Belov, Katherine
Koala Genome Survey: An Open Data Resource to Improve Conservation Planning
title Koala Genome Survey: An Open Data Resource to Improve Conservation Planning
title_full Koala Genome Survey: An Open Data Resource to Improve Conservation Planning
title_fullStr Koala Genome Survey: An Open Data Resource to Improve Conservation Planning
title_full_unstemmed Koala Genome Survey: An Open Data Resource to Improve Conservation Planning
title_short Koala Genome Survey: An Open Data Resource to Improve Conservation Planning
title_sort koala genome survey: an open data resource to improve conservation planning
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048327/
https://www.ncbi.nlm.nih.gov/pubmed/36980819
http://dx.doi.org/10.3390/genes14030546
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