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Accumulation of STR-Loci Aberrations in Subclones of Jurkat Cell Line as a Model of Tumor Clonal Evolution

Many genetic markers are known to distinguish tumor cells from normal. Genetic lesions found at disease onset often belong to a predominant tumor clone, and further observation makes it possible to assess the fate of this clone during therapy. However, minor clones escape monitoring and become unide...

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Detalles Bibliográficos
Autores principales: Risinskaya, Natalya, Glinshchikova, Olga, Makarik, Tatiana, Kozhevnikova, Yana, Chabaeva, Julia, Kulikov, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048572/
https://www.ncbi.nlm.nih.gov/pubmed/36980843
http://dx.doi.org/10.3390/genes14030571