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Qbd-Based Approach to Optimize Niosomal Gel of Levosulpiride for Transdermal Drug Delivery

Poor aqueous solubility besides extensive hepatic first effect significantly decreases the oral absorption of levosulpiride, which in turn minimizes its therapeutic effectiveness. Niosomes have been extensively investigated as a transdermal vesicular nanocarrier to increase the delivery of low perme...

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Detalles Bibliográficos
Autores principales: Alnaim, Ahmed S., Shah, Hiral, Nair, Anroop B., Mewada, Vivek, Patel, Smit, Jacob, Shery, Aldhubiab, Bandar, Morsy, Mohamed A., Almuqbil, Rashed M., Shinu, Pottathil, Shah, Jigar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048649/
https://www.ncbi.nlm.nih.gov/pubmed/36975662
http://dx.doi.org/10.3390/gels9030213