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Dimeric Ankyrin with Inverted Module Promotes Bifunctional Property in Capturing Capsid to Impede HIV-1 Replication

Several anti-HIV scaffolds have been proposed as complementary treatments to highly active antiretroviral therapy. Ank(GAG)1D4, a designed ankyrin repeat protein, formerly demonstrated anti-HIV-1 replication by interfering with HIV-1 Gag polymerization. However, the improvement of the effectiveness...

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Detalles Bibliográficos
Autores principales: Juntit, On-anong, Sornsuwan, Kanokporn, Wisitponchai, Tanchanok, Sanghiran Lee, Vannajan, Sakkhachornphop, Supachai, Yasamut, Umpa, Tayapiwatana, Chatchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048781/
https://www.ncbi.nlm.nih.gov/pubmed/36982337
http://dx.doi.org/10.3390/ijms24065266

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