C-Terminal Truncated HBx Facilitates Oncogenesis by Modulating Cell Cycle and Glucose Metabolism in FXR-Deficient Hepatocellular Carcinoma

Farnesoid X receptor (FXR) is a nuclear receptor known to play protective roles in anti-hepatocarcinogenesis and regulation of the basal metabolism of glucose, lipids, and bile acids. FXR expression is low or absent in HBV-associated hepatocarcinogenesis. Full-length HBx and HBx C-terminal truncatio...

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Autores principales: Wu, Xuejun, Ni, Zhengzhong, Song, Tiantian, Lv, Wenya, Chen, Yan, Huang, Danmei, Xie, Yangmin, Huang, Weiyi, Niu, Yongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048952/
https://www.ncbi.nlm.nih.gov/pubmed/36982249
http://dx.doi.org/10.3390/ijms24065174

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