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Case Report: Acute Intoxication from Phosphine Inhalation

Aluminum phosphide is a highly effective insecticide for fumigation in granaries and is often used in rural grain storage. However, people’s awareness of its toxicity is not strong. A case of acute inhalation toxicity of phosphine caused by the use of aluminum phosphide to fumigate a granary is repo...

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Autores principales: Shi, Longke, Jian, Tianzi, Tao, Yiming, Li, Yaqian, Yu, Guangcai, Zhao, Liwen, Wen, Zixin, Kan, Baotian, Jian, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048961/
https://www.ncbi.nlm.nih.gov/pubmed/36981930
http://dx.doi.org/10.3390/ijerph20065021
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author Shi, Longke
Jian, Tianzi
Tao, Yiming
Li, Yaqian
Yu, Guangcai
Zhao, Liwen
Wen, Zixin
Kan, Baotian
Jian, Xiangdong
author_facet Shi, Longke
Jian, Tianzi
Tao, Yiming
Li, Yaqian
Yu, Guangcai
Zhao, Liwen
Wen, Zixin
Kan, Baotian
Jian, Xiangdong
author_sort Shi, Longke
collection PubMed
description Aluminum phosphide is a highly effective insecticide for fumigation in granaries and is often used in rural grain storage. However, people’s awareness of its toxicity is not strong. A case of acute inhalation toxicity of phosphine caused by the use of aluminum phosphide to fumigate a granary is reported here. The case presented with aspiration pneumonia and acute left heart failure. The patient was cured using comprehensive life support treatment, including respiratory support, antiarrhythmic treatment, and blood pressure maintenance with vasoactive drugs. There is no specific antidote for phosphine poisoning at present, and the comprehensive application of restricted fluid resuscitation, high-dose glucocorticoid shock, vasoactive drugs and bedside hemofiltration is significant in improving the prognosis of patients. It is also important to remind people to pay attention to their own protection in the process of using aluminum phosphide.
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spelling pubmed-100489612023-03-29 Case Report: Acute Intoxication from Phosphine Inhalation Shi, Longke Jian, Tianzi Tao, Yiming Li, Yaqian Yu, Guangcai Zhao, Liwen Wen, Zixin Kan, Baotian Jian, Xiangdong Int J Environ Res Public Health Case Report Aluminum phosphide is a highly effective insecticide for fumigation in granaries and is often used in rural grain storage. However, people’s awareness of its toxicity is not strong. A case of acute inhalation toxicity of phosphine caused by the use of aluminum phosphide to fumigate a granary is reported here. The case presented with aspiration pneumonia and acute left heart failure. The patient was cured using comprehensive life support treatment, including respiratory support, antiarrhythmic treatment, and blood pressure maintenance with vasoactive drugs. There is no specific antidote for phosphine poisoning at present, and the comprehensive application of restricted fluid resuscitation, high-dose glucocorticoid shock, vasoactive drugs and bedside hemofiltration is significant in improving the prognosis of patients. It is also important to remind people to pay attention to their own protection in the process of using aluminum phosphide. MDPI 2023-03-12 /pmc/articles/PMC10048961/ /pubmed/36981930 http://dx.doi.org/10.3390/ijerph20065021 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Shi, Longke
Jian, Tianzi
Tao, Yiming
Li, Yaqian
Yu, Guangcai
Zhao, Liwen
Wen, Zixin
Kan, Baotian
Jian, Xiangdong
Case Report: Acute Intoxication from Phosphine Inhalation
title Case Report: Acute Intoxication from Phosphine Inhalation
title_full Case Report: Acute Intoxication from Phosphine Inhalation
title_fullStr Case Report: Acute Intoxication from Phosphine Inhalation
title_full_unstemmed Case Report: Acute Intoxication from Phosphine Inhalation
title_short Case Report: Acute Intoxication from Phosphine Inhalation
title_sort case report: acute intoxication from phosphine inhalation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10048961/
https://www.ncbi.nlm.nih.gov/pubmed/36981930
http://dx.doi.org/10.3390/ijerph20065021
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