Morphology-Dependent Interactions between α-Synuclein Monomers and Fibrils

Amyloid fibrils may adopt different morphologies depending on the solution conditions and the protein sequence. Here, we show that two chemically identical but morphologically distinct α-synuclein fibrils can form under identical conditions. This was observed by nuclear magnetic resonance (NMR), cir...

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Detalles Bibliográficos
Autores principales: Pálmadóttir, Tinna, Waudby, Christopher A., Bernfur, Katja, Christodoulou, John, Linse, Sara, Malmendal, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049171/
https://www.ncbi.nlm.nih.gov/pubmed/36982264
http://dx.doi.org/10.3390/ijms24065191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049171/
https://www.ncbi.nlm.nih.gov/pubmed/36982264
http://dx.doi.org/10.3390/ijms24065191

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