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Morphology-Dependent Interactions between α-Synuclein Monomers and Fibrils
Amyloid fibrils may adopt different morphologies depending on the solution conditions and the protein sequence. Here, we show that two chemically identical but morphologically distinct α-synuclein fibrils can form under identical conditions. This was observed by nuclear magnetic resonance (NMR), cir...
Autores principales: | Pálmadóttir, Tinna, Waudby, Christopher A., Bernfur, Katja, Christodoulou, John, Linse, Sara, Malmendal, Anders |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049171/ https://www.ncbi.nlm.nih.gov/pubmed/36982264 http://dx.doi.org/10.3390/ijms24065191 |
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