Cargando…

New Insights into the Role of Synovial Fibroblasts Leading to Joint Destruction in Rheumatoid Arthritis

Rheumatoid arthritis (RA), one of the most common autoimmune diseases, is characterized by multiple-joint synovitis with subsequent destruction of bone and cartilage. The excessive autoimmune responses cause an imbalance in bone metabolism, promoting bone resorption and inhibiting bone formation. Pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matsuda, Kotaro, Shiba, Naoto, Hiraoka, Koji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049180/ https://www.ncbi.nlm.nih.gov/pubmed/36982247 http://dx.doi.org/10.3390/ijms24065173

Ejemplares similares

Fibroblast biology: Synovial fibroblasts in rheumatoid arthritis - leading role or chorus line?
por: Kontoyiannis, Dimitris, et al.
Publicado: (2000)

New insights into integrin signalling: implications for rheumatoid arthritis synovial fibroblasts
por: Pap, Thomas
Publicado: (2003)

RNA-seq analysis of synovial fibroblasts brings new insights into rheumatoid arthritis
por: Heruth, Daniel P, et al.
Publicado: (2012)

New Insights From Single-Cell Sequencing Data: Synovial Fibroblasts and Synovial Macrophages in Rheumatoid Arthritis
por: Cheng, Liyun, et al.
Publicado: (2021)

Activation of Synovial Fibroblasts in Rheumatoid Arthritis
por: Gay, Steffen, et al.
Publicado: (2000)

Matrix Metalloproteinase-9 Level in Synovial Fluid—Association with Joint Destruction in Early Rheumatoid Arthritis
por: Stojanovic, Sonja K., et al.
Publicado: (2023)

Fibroblast biology: Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis
por: Pap, Thomas, et al.
Publicado: (2000)

EGFP gene transfection into the synovial joint tissues of rats with rheumatoid arthritis by ultrasound-mediated microbubble destruction
por: JING, XIANG-XIANG, et al.
Publicado: (2014)

Possibility of inhibiting arthritis and joint destruction by SSEA-3 positive cells derived from synovial tissue in rheumatoid arthritis
por: Kurose, Rie, et al.
Publicado: (2017)

Myricitrin inhibits fibroblast-like synoviocyte-mediated rheumatoid synovial inflammation and joint destruction by targeting AIM2
por: Shen, Chuyu, et al.
Publicado: (2022)

Cells of the synovium in rheumatoid arthritis. Synovial fibroblasts
por: Müller-Ladner, Ulf, et al.
Publicado: (2007)

Evidence for synovial fibroblasts spreading rheumatoid arthritis
por: Müller-Ladner, Ulf, et al.
Publicado: (2012)

Multiomics landscape of synovial fibroblasts in rheumatoid arthritis
por: Tsuchiya, Haruka, et al.
Publicado: (2021)

Drivers of heterogeneity in synovial fibroblasts in rheumatoid arthritis
por: Smith, Melanie H., et al.
Publicado: (2023)

Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction
por: Pap, Thomas, et al.
Publicado: (2000)

Role of LIGHT in the pathogenesis of joint destruction in rheumatoid arthritis
por: Sabokbar, Afsie, et al.
Publicado: (2017)

Structural cartilage damage attracts circulating rheumatoid arthritis synovial fibroblasts into affected joints
por: Hillen, Jan, et al.
Publicado: (2017)

Targeting Activated Synovial Fibroblasts in Rheumatoid Arthritis by Peficitinib
por: Diller, Magnus, et al.
Publicado: (2019)

Editorial: Immunomodulatory Functions of Fibroblast-like Synoviocytes in Joint Inflammation and Destruction during Rheumatoid Arthritis
por: Xu, Hanshi, et al.
Publicado: (2020)

Role of synovial fibroblast subsets across synovial pathotypes in rheumatoid arthritis: a deconvolution analysis
por: Micheroli, Raphael, et al.
Publicado: (2022)

Oral steroid decreases the progression of joint destruction of large joints in the lower extremities in rheumatoid arthritis
por: Doi, K., et al.
Publicado: (2019)

Differential gene expression of proliferating synovial fibroblasts in rheumatoid arthritis
por: Masuda, KM, et al.
Publicado: (2002)

Transcriptional response to hypoxia of normal and rheumatoid arthritis synovial fibroblasts
por: Del Rey, M J, et al.
Publicado: (2010)

The epigenome of synovial fibroblasts: an underestimated therapeutic target in rheumatoid arthritis
por: Frank-Bertoncelj, Mojca, et al.
Publicado: (2014)

Profiling drugs for rheumatoid arthritis that inhibit synovial fibroblast activation
por: Jones, Douglas S., et al.
Publicado: (2016)

Marker Genes Change of Synovial Fibroblasts in Rheumatoid Arthritis Patients
por: Liao, Lifen, et al.
Publicado: (2021)

Association of autophagy to the phenotypic transformation of synovial fibroblasts in rheumatoid arthritis
por: Kondo, Naoki
Publicado: (2022)

Mosaic chromosomal aberrations in synovial fibroblasts of patients with rheumatoid arthritis, osteoarthritis, and other inflammatory joint diseases
por: Kinne, Raimund W, et al.
Publicado: (2001)

NR1D1 modulates synovial inflammation and bone destruction in rheumatoid arthritis
por: Liu, Hui, et al.
Publicado: (2020)

Time-averaged disease activity fits better joint destruction in rheumatoid arthritis
por: Tsuji, Hideaki, et al.
Publicado: (2017)

Gene therapy in rheumatoid arthritis: how to target joint destruction?
por: Pap, Thomas, et al.
Publicado: (1999)

The invasiveness of fibroblast-like synoviocytes is of relevance for the rate of joint destruction in patients with rheumatoid arthritis and is a patient characteristic
por: Tolboom, TCA, et al.
Publicado: (2005)

Crosstalk between synovial fibroblasts and T lymphocytes in rheumatoid arthritis: effect of methotrexate
por: Miranda, E, et al.
Publicado: (2003)

Cigarette smoke downregulates HDAC2 in rheumatoid arthritis synovial fibroblasts
por: Engler, Anna, et al.
Publicado: (2012)

Molecular profile of synovial fibroblasts in rheumatoid arthritis depends on the stage of proliferation
por: Masuda, Kimio, et al.
Publicado: (2002)

Optimized “In Vitro” Culture Conditions for Human Rheumatoid Arthritis Synovial Fibroblasts
por: Casnici, Claudia, et al.
Publicado: (2014)

MicroRNAs interfere with DNA methylation in rheumatoid arthritis synovial fibroblasts
por: Gaur, Niharika, et al.
Publicado: (2016)

Cannabidiol (CBD): a killer for inflammatory rheumatoid arthritis synovial fibroblasts
por: Lowin, Torsten, et al.
Publicado: (2020)

Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability
por: Ge, Xiangyu, et al.
Publicado: (2021)

The mammalian target of rapamycin contributes to synovial fibroblast pathogenicity in rheumatoid arthritis
por: Barker, Brianne E., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_1j7dseho1brilnukp3790b1tcn