Prognostic Value of Monocarboxylate Transporter 1 Overexpression in Cancer: A Systematic Review

Energy production by cancer is driven by accelerated glycolysis, independently of oxygen levels, which results in increased lactate production. Lactate is shuttled to and from cancer cells via monocarboxylate transporters (MCTs). MCT1 works both as an importer and an extruder of lactate, being widel...

Descripción completa

Detalles Bibliográficos
Autores principales: Silva, Ana, Cerqueira, Mónica Costa, Rosa, Beatriz, Sobral, Catarina, Pinto-Ribeiro, Filipa, Costa, Marta Freitas, Baltazar, Fátima, Afonso, Julieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049181/
https://www.ncbi.nlm.nih.gov/pubmed/36982217
http://dx.doi.org/10.3390/ijms24065141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049181/
https://www.ncbi.nlm.nih.gov/pubmed/36982217
http://dx.doi.org/10.3390/ijms24065141

Ejemplares similares