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Prognostic Value of Monocarboxylate Transporter 1 Overexpression in Cancer: A Systematic Review
Energy production by cancer is driven by accelerated glycolysis, independently of oxygen levels, which results in increased lactate production. Lactate is shuttled to and from cancer cells via monocarboxylate transporters (MCTs). MCT1 works both as an importer and an extruder of lactate, being widel...
Autores principales: | Silva, Ana, Cerqueira, Mónica Costa, Rosa, Beatriz, Sobral, Catarina, Pinto-Ribeiro, Filipa, Costa, Marta Freitas, Baltazar, Fátima, Afonso, Julieta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049181/ https://www.ncbi.nlm.nih.gov/pubmed/36982217 http://dx.doi.org/10.3390/ijms24065141 |
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