Development of Highly Sensitive Digital Droplet PCR for Detection of cKIT Mutations in Circulating Free DNA That Mediate Resistance to TKI Treatment for Gastrointestinal Stromal Tumor (GIST)

Background: Mutations in cKIT or PDGFRA are found in up to 90% of patients with gastrointestinal stromal tumors (GISTs). Previously, we described the design, validation, and clinical performance of a digital droplet (dd)PCR assay panel for the detection of imatinib-sensitive cKIT and PDFGRA mutation...

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Detalles Bibliográficos
Autores principales: Rassner, Michael, Waldeck, Silvia, Follo, Marie, Jilg, Stefanie, Philipp, Ulrike, Jolic, Martina, Wehrle, Julius, Jost, Philipp J., Peschel, Christian, Illert, Anna Lena, Duyster, Justus, Scherer, Florian, von Bubnoff, Nikolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049191/
https://www.ncbi.nlm.nih.gov/pubmed/36982486
http://dx.doi.org/10.3390/ijms24065411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049191/
https://www.ncbi.nlm.nih.gov/pubmed/36982486
http://dx.doi.org/10.3390/ijms24065411

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