LOX-1 Activation by oxLDL Induces AR and AR-V7 Expression via NF-κB and STAT3 Signaling Pathways Reducing Enzalutamide Cytotoxic Effects

The oxidized low-density lipoprotein receptor 1 (LOX-1) is one of the most important receptors for modified LDLs, such as oxidated (oxLDL) and acetylated (acLDL) low-density lipoprotein. LOX-1 and oxLDL are fundamental in atherosclerosis, where oxLDL/LOX1 promotes ROS generation and NF-κB activation...

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Detalles Bibliográficos
Autores principales: Duprat, Felix, Robles, Catalina, Castillo, María Paz, Rivas, Yerko, Mondaca, Marcela, Jara, Nery, Roa, Francisco, Bertinat, Romina, Toledo, Jorge, Paz, Cristian, González-Chavarría, Iván
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049196/
https://www.ncbi.nlm.nih.gov/pubmed/36982155
http://dx.doi.org/10.3390/ijms24065082

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