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Long-Term Evaluation of Retinal Morphology and Function in Rosa26-Cas9 Knock-In Mice

The CRISPR/Cas9 system is a robust, efficient, and cost-effective gene editing tool widely adopted in translational studies of ocular diseases. However, in vivo CRISPR-based editing in animal models poses challenges such as the efficient delivery of the CRISPR components in viral vectors with limite...

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Detalles Bibliográficos
Autores principales: Mohan, Kabhilan, Dubey, Sushil Kumar, Jung, Kyungsik, Dubey, Rashmi, Wang, Qing Jun, Prajapati, Subhash, Roney, Jacob, Abney, Jennifer, Kleinman, Mark Ellsworth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049241/
https://www.ncbi.nlm.nih.gov/pubmed/36982266
http://dx.doi.org/10.3390/ijms24065186

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