Anti-Inflammatory Effects and Photo- and Neuro-Protective Properties of BIO203, a New Amide Conjugate of Norbixin, in Development for the Treatment of Age-Related Macular Degeneration (AMD)

9′-cis-norbixin (norbixin/BIO201) protects RPE cells against phototoxicity induced by blue light and N-retinylidene-N-retinylethanolamine (A2E) in vitro and preserves visual functions in animal models of age-related macular degeneration (AMD) in vivo. The purpose of this study was to examine the mod...

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Detalles Bibliográficos
Autores principales: Fontaine, Valérie, Balducci, Christine, Dinan, Laurence, Monteiro, Elodie, Boumedine, Thinhinane, Fournié, Mylène, Nguyen, Vincent, Guibout, Louis, Clatot, Justine, Latil, Mathilde, Veillet, Stanislas, Sahel, José-Alain, Lafont, René, Dilda, Pierre J., Camelo, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049354/
https://www.ncbi.nlm.nih.gov/pubmed/36982372
http://dx.doi.org/10.3390/ijms24065296

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