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DHEA and Its Metabolites Reduce the Cytokines Involved in the Inflammatory Response and Fibrosis in Primary Biliary Cholangitis

Dehydroepiandrosterone (DHEA) is an abundant steroid and precursor of sex hormones. During aging, the reduction in DHEA synthesis causes a significant depletion of estrogens and androgens in different organs, such as the ovaries, brain, and liver. Primary Biliary Cholangitis (PBC) is a cholestatic l...

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Detalles Bibliográficos
Autores principales: Blatkiewicz, Małgorzata, Sielatycka, Katarzyna, Piotrowska, Katarzyna, Kilańczyk, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049419/
https://www.ncbi.nlm.nih.gov/pubmed/36982376
http://dx.doi.org/10.3390/ijms24065301

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