S100B Expression Plays a Crucial Role in Cytotoxicity, Reactive Oxygen Species Generation and Nitric Oxide Synthase Activation Induced by Amyloid β-Protein in an Astrocytoma Cell Line

S100B is an astrocytic cytokine that has been shown to be involved in several neurodegenerative diseases. We used an astrocytoma cell line (U373 MG) silenced for S100B, and stimulated it with amyloid beta-peptide (Aβ) as a known paradigm factor for astrocyte activation, and showed that the ability o...

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Detalles Bibliográficos
Autores principales: Clementi, Maria Elisabetta, Sampaolese, Beatrice, Di Sante, Gabriele, Ria, Francesco, Di Liddo, Rosa, Romano Spica, Vincenzo, Michetti, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049549/
https://www.ncbi.nlm.nih.gov/pubmed/36982288
http://dx.doi.org/10.3390/ijms24065213

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