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Metformin Attenuates the Inflammatory Response via the Regulation of Synovial M1 Macrophage in Osteoarthritis

Osteoarthritis (OA), the most common chronic inflammatory joint disease, is characterized by progressive cartilage degeneration, subchondral bone sclerosis, synovitis, and osteophyte formation. Metformin, a hypoglycemic agent used in the treatment of type 2 diabetes, has been evidenced to have anti-...

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Detalles Bibliográficos
Autores principales: Zheng, Meng, Zhu, Yuanli, Wei, Kang, Pu, Hongxu, Peng, Renpeng, Xiao, Jun, Liu, Changyu, Sun, Xuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049635/
https://www.ncbi.nlm.nih.gov/pubmed/36982442
http://dx.doi.org/10.3390/ijms24065355