Cargando…
New Insights into the Modification of the Non-Core Metabolic Pathway of Steroids in Mycolicibacterium and the Application of Fermentation Biotechnology in C-19 Steroid Production
Androsta-4-ene-3,17-dione (AD), androsta-1,4-diene-3,17-dione (ADD), and 9α-hydroxy-4-androstene-3,17-dione (9-OHAD), which belong to C-19 steroids, are critical steroid-based drug intermediates. The biotransformation of phytosterols into C-19 steroids by Mycolicibacterium cell factories is the core...
Autores principales: | Zhang, Yang, Xiao, Peiyao, Pan, Delong, Zhou, Xiuling |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049677/ https://www.ncbi.nlm.nih.gov/pubmed/36982310 http://dx.doi.org/10.3390/ijms24065236 |
Ejemplares similares
-
New Insights on Steroid Biotechnology
por: Fernández-Cabezón, Lorena, et al.
Publicado: (2018) -
Engineering the Steroid Hydroxylating System from Cochliobolus lunatus in Mycolicibacterium smegmatis
por: Felpeto-Santero, Carmen, et al.
Publicado: (2021) -
Unravelling and engineering an operon involved in the side-chain degradation of sterols in Mycolicibacterium neoaurum for the production of steroid synthons
por: Zhao, Yun-Qiu, et al.
Publicado: (2023) -
Reconstruction of the Steroid 1(2)-Dehydrogenation System from Nocardioides simplex VKM Ac-2033D in Mycolicibacterium Hosts
por: Fufaeva, Svetlana R., et al.
Publicado: (2023) -
Production of 11α‐hydroxysteroids from sterols in a single fermentation step by Mycolicibacterium smegmatis
por: Felpeto‐Santero, Carmen, et al.
Publicado: (2021)