Deregulation of Astroglial TASK-1 K(+) Channel Decreases the Responsiveness to Perampanel-Induced AMPA Receptor Inhibition in Chronic Epilepsy Rats

Tandem of P domains in a weak inwardly rectifying K(+) channel (TWIK)-related acid sensitive K(+)-1 channel (TASK-1) is activated under extracellular alkaline conditions (pH 7.2–8.2), which are upregulated in astrocytes (particularly in the CA1 region) of the hippocampi of patients with temporal lob...

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Detalles Bibliográficos
Autores principales: Lee, Duk-Shin, Kim, Tae-Hyun, Park, Hana, Kang, Tae-Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049714/
https://www.ncbi.nlm.nih.gov/pubmed/36982567
http://dx.doi.org/10.3390/ijms24065491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049714/
https://www.ncbi.nlm.nih.gov/pubmed/36982567
http://dx.doi.org/10.3390/ijms24065491

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