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Deregulation of Astroglial TASK-1 K(+) Channel Decreases the Responsiveness to Perampanel-Induced AMPA Receptor Inhibition in Chronic Epilepsy Rats
Tandem of P domains in a weak inwardly rectifying K(+) channel (TWIK)-related acid sensitive K(+)-1 channel (TASK-1) is activated under extracellular alkaline conditions (pH 7.2–8.2), which are upregulated in astrocytes (particularly in the CA1 region) of the hippocampi of patients with temporal lob...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049714/ https://www.ncbi.nlm.nih.gov/pubmed/36982567 http://dx.doi.org/10.3390/ijms24065491 |