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Legumain Functions as a Transient TrkB Sheddase

While primarily found in endo-lysosomal compartments, the cysteine protease legumain can also translocate to the cell surface if stabilized by the interaction with the RGD-dependent integrin receptor αVβ3. Previously, it has been shown that legumain expression is inversely related to BDNF-TrkB activ...

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Detalles Bibliográficos
Autores principales: Holzner, Christoph, Böttinger, Katharina, Blöchl, Constantin, Huber, Christian G., Dahms, Sven O., Dall, Elfriede, Brandstetter, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049731/
https://www.ncbi.nlm.nih.gov/pubmed/36982466
http://dx.doi.org/10.3390/ijms24065394