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Legumain Functions as a Transient TrkB Sheddase
While primarily found in endo-lysosomal compartments, the cysteine protease legumain can also translocate to the cell surface if stabilized by the interaction with the RGD-dependent integrin receptor αVβ3. Previously, it has been shown that legumain expression is inversely related to BDNF-TrkB activ...
Autores principales: | Holzner, Christoph, Böttinger, Katharina, Blöchl, Constantin, Huber, Christian G., Dahms, Sven O., Dall, Elfriede, Brandstetter, Hans |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049731/ https://www.ncbi.nlm.nih.gov/pubmed/36982466 http://dx.doi.org/10.3390/ijms24065394 |
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