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GENLIB: new function to simulate haplotype transmission in large complex genealogies

SUMMARY: Founder populations with deep genealogical data are well suited for investigating genetic variants contributing to diseases. Here, we present a major update of the genealogical analysis R package GENLIB, centered around a new function which can simulate the transmission of haplotypes from f...

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Detalles Bibliográficos
Autores principales: Rakesh, Mohan, Vézina, Hélène, Laprise, Catherine, Freeman, Ellen E, Burkett, Kelly M, Roy-Gagnon, Marie-Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10049784/
https://www.ncbi.nlm.nih.gov/pubmed/36929931
http://dx.doi.org/10.1093/bioinformatics/btad136