Inhibition of the epigenetically activated miR-483-5p/IGF-2 pathway results in rapid loss of meningioma tumor cell viability

PURPOSE: Meningioma is the most common primary central nervous system tumor often causing serious complications, and presently no medical treatment is available. The goal of this study was to discover miRNAs dysregulated in meningioma, and explore miRNA-associated pathways amenable for therapeutic i...

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Detalles Bibliográficos
Autores principales: Uhlmann, Erik J., Mackel, Charles E., Deforzh, Evgeny, Rabinovsky, Rosalia, Brastianos, Priscilla K., Varma, Hemant, Vega, Rafael A., Krichevsky, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050031/
https://www.ncbi.nlm.nih.gov/pubmed/36809604
http://dx.doi.org/10.1007/s11060-023-04264-z

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