The role of maternal age & birth order on the development of unilateral and bilateral retinoblastoma: a multicentre study

BACKGROUND/OBJECTIVES: Retinoblastoma is a common childhood intraocular malignancy, the bilateral form of which most commonly results from a de novo germline pathogenic variant in the RB1 gene. Both advanced maternal age and decreasing birth order are known to increase the risk of de novo germline p...

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Detalles Bibliográficos
Autores principales: Lloyd, Philippa, Westcott, Mark, Kaliki, Swathi, Ji, Xunda, Zou, Yihua, Rashid, Riffat, Sultana, Sadia, Sherief, Sadik Taju, Cassoux, Nathalie, Diaz Coronado, Rosdali Yesenia, Garcia Leon, Juan Luis, López, Arturo Manuel Zapata, Polyakov, Vladimir G., Ushakova, Tatiana L., Roy, Soma Rani, Ahmad, Alia, Harby, Lamis Al, Berry, Jesse L., Kim, Jonathan, Polski, Ashley, Astbury, Nicholas J., Bascaran, Covadonga, Blum, Sharon, Bowman, Richard, Burton, Matthew J., Foster, Allen, Gomel, Nir, Keren-Froim, Naama, Madgar, Shiran, Stacey, Andrew W., Mohamed, Ashik, Zondervan, Marcia, Sagoo, Mandeep S., Fabian, Ido Didi, Reddy, M. Ashwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050160/
https://www.ncbi.nlm.nih.gov/pubmed/35361938
http://dx.doi.org/10.1038/s41433-022-01992-w

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