External to internal cranial perfusion shifts during simulated weightlessness: Results from a randomized cross-over trial

The exact pathophysiology of the spaceflight-associated neuro-ocular syndrome (SANS) has so far not been completely elucidated. In this study we assessed the effect of acute head-down tilt position on the mean flow of the intra- and extracranial vessels. Our results suggest a shift from the external...

Descripción completa

Detalles Bibliográficos
Autores principales: Boschert, Alessa L., Gauger, Peter, Bach, Anja, Gerlach, Darius, Johannes, Bernd, Jordan, Jens, Li, Zhili, Elmenhorst, David, Bauer, Andreas, Marshall-Goebel, Karina, Tank, Jens, Zange, Jochen, Rittweger, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050182/
https://www.ncbi.nlm.nih.gov/pubmed/36977696
http://dx.doi.org/10.1038/s41526-023-00267-2
Descripción
Sumario:The exact pathophysiology of the spaceflight-associated neuro-ocular syndrome (SANS) has so far not been completely elucidated. In this study we assessed the effect of acute head-down tilt position on the mean flow of the intra- and extracranial vessels. Our results suggest a shift from the external to the internal system that might play an important role in the pathomechanism of SANS.

Ejemplares similares