External to internal cranial perfusion shifts during simulated weightlessness: Results from a randomized cross-over trial

The exact pathophysiology of the spaceflight-associated neuro-ocular syndrome (SANS) has so far not been completely elucidated. In this study we assessed the effect of acute head-down tilt position on the mean flow of the intra- and extracranial vessels. Our results suggest a shift from the external...

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Autores principales: Boschert, Alessa L., Gauger, Peter, Bach, Anja, Gerlach, Darius, Johannes, Bernd, Jordan, Jens, Li, Zhili, Elmenhorst, David, Bauer, Andreas, Marshall-Goebel, Karina, Tank, Jens, Zange, Jochen, Rittweger, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050182/
https://www.ncbi.nlm.nih.gov/pubmed/36977696
http://dx.doi.org/10.1038/s41526-023-00267-2
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author Boschert, Alessa L.
Gauger, Peter
Bach, Anja
Gerlach, Darius
Johannes, Bernd
Jordan, Jens
Li, Zhili
Elmenhorst, David
Bauer, Andreas
Marshall-Goebel, Karina
Tank, Jens
Zange, Jochen
Rittweger, Jörn
author_facet Boschert, Alessa L.
Gauger, Peter
Bach, Anja
Gerlach, Darius
Johannes, Bernd
Jordan, Jens
Li, Zhili
Elmenhorst, David
Bauer, Andreas
Marshall-Goebel, Karina
Tank, Jens
Zange, Jochen
Rittweger, Jörn
author_sort Boschert, Alessa L.
collection PubMed
description The exact pathophysiology of the spaceflight-associated neuro-ocular syndrome (SANS) has so far not been completely elucidated. In this study we assessed the effect of acute head-down tilt position on the mean flow of the intra- and extracranial vessels. Our results suggest a shift from the external to the internal system that might play an important role in the pathomechanism of SANS.
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spelling pubmed-100501822023-03-30 External to internal cranial perfusion shifts during simulated weightlessness: Results from a randomized cross-over trial Boschert, Alessa L. Gauger, Peter Bach, Anja Gerlach, Darius Johannes, Bernd Jordan, Jens Li, Zhili Elmenhorst, David Bauer, Andreas Marshall-Goebel, Karina Tank, Jens Zange, Jochen Rittweger, Jörn NPJ Microgravity Brief Communication The exact pathophysiology of the spaceflight-associated neuro-ocular syndrome (SANS) has so far not been completely elucidated. In this study we assessed the effect of acute head-down tilt position on the mean flow of the intra- and extracranial vessels. Our results suggest a shift from the external to the internal system that might play an important role in the pathomechanism of SANS. Nature Publishing Group UK 2023-03-28 /pmc/articles/PMC10050182/ /pubmed/36977696 http://dx.doi.org/10.1038/s41526-023-00267-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Brief Communication
Boschert, Alessa L.
Gauger, Peter
Bach, Anja
Gerlach, Darius
Johannes, Bernd
Jordan, Jens
Li, Zhili
Elmenhorst, David
Bauer, Andreas
Marshall-Goebel, Karina
Tank, Jens
Zange, Jochen
Rittweger, Jörn
External to internal cranial perfusion shifts during simulated weightlessness: Results from a randomized cross-over trial
title External to internal cranial perfusion shifts during simulated weightlessness: Results from a randomized cross-over trial
title_full External to internal cranial perfusion shifts during simulated weightlessness: Results from a randomized cross-over trial
title_fullStr External to internal cranial perfusion shifts during simulated weightlessness: Results from a randomized cross-over trial
title_full_unstemmed External to internal cranial perfusion shifts during simulated weightlessness: Results from a randomized cross-over trial
title_short External to internal cranial perfusion shifts during simulated weightlessness: Results from a randomized cross-over trial
title_sort external to internal cranial perfusion shifts during simulated weightlessness: results from a randomized cross-over trial
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050182/
https://www.ncbi.nlm.nih.gov/pubmed/36977696
http://dx.doi.org/10.1038/s41526-023-00267-2
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