Partially hydrolyzed guar gum increased colonic mucus layer in mice via succinate-mediated MUC2 production

Colonic mucus layers protect intestinal tissues against intestinal bacteria. We investigated the effects of dietary fiber and its metabolites on mucus production in the colonic mucosa. Mice were fed a partially hydrolyzed guar gum (PHGG)-containing diet and a fiber-free diet (FFD). The colon mucus l...

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Detalles Bibliográficos
Autores principales: Kajiwara-Kubota, Mariko, Uchiyama, Kazuhiko, Asaeda, Kohei, Kobayashi, Reo, Hashimoto, Hikaru, Yasuda, Takeshi, Sugino, Satoshi, Sugaya, Takeshi, Hirai, Yasuko, Mizushima, Katsura, Doi, Toshifumi, Inoue, Ken, Dohi, Osamu, Yoshida, Naohisa, Ishikawa, Takeshi, Takagi, Tomohisa, Konishi, Hideyuki, Inoue, Ryo, Itoh, Yoshito, Naito, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050209/
https://www.ncbi.nlm.nih.gov/pubmed/36977699
http://dx.doi.org/10.1038/s41538-023-00184-4

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