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High-throughput screening of mutations affecting SARS-CoV-2 spike functions

The spike (S) protein of SARS-CoV-2, which is undergoing rapid evolution, plays crucial roles in viral immune escape, infectivity, and transmissibility. To gain clinical insight, Dadonaite et al. developed a novel deep mutational scanning (DMS) platform for mapping the effects of S protein mutations...

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Detalles Bibliográficos
Autores principales:	Xia, Shuai, Liu, Zezhong, Jiang, Shibo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2023
Materias:	Spotlight
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050277/ https://www.ncbi.nlm.nih.gov/pubmed/37031063 http://dx.doi.org/10.1016/j.it.2023.03.010

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