METTL3 enhances pancreatic ductal adenocarcinoma progression and gemcitabine resistance through modifying DDX23 mRNA N6 adenosine methylation

The aim of the present study was to clarify the mechanism of how METTL3 regulated pancreatic ductal adenocarcinoma (PDAC) progression by m6A modification of its downstream target mRNA and signaling pathway. Immunoblotting and qRT-PCR assays was employed to determine the expression levels of METTL3....

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Detalles Bibliográficos
Autores principales: Lin, Chengjie, Li, Ting, Wang, Yan, Lai, Shihui, Huang, Yue, Guo, Zhenyun, Zhang, Xiang, Weng, Shangeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050319/
https://www.ncbi.nlm.nih.gov/pubmed/36977668
http://dx.doi.org/10.1038/s41419-023-05715-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050319/
https://www.ncbi.nlm.nih.gov/pubmed/36977668
http://dx.doi.org/10.1038/s41419-023-05715-1

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