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Adrenergic receptor signaling regulates the CD40-receptor mediated anti-tumor immunity
INTRODUCTION: Anti-CD40 agonistic antibody (αCD40), an activator of dendritic cells (DC) can enhance antigen presentation and activate cytotoxic T-cells against poorly immunogenic tumors. However, cancer immunotherapy trials also suggest that αCD40 is only moderately effective in patients, falling s...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050348/ https://www.ncbi.nlm.nih.gov/pubmed/37006295 http://dx.doi.org/10.3389/fimmu.2023.1141712 |