Cargando…

Adrenergic receptor signaling regulates the CD40-receptor mediated anti-tumor immunity

INTRODUCTION: Anti-CD40 agonistic antibody (αCD40), an activator of dendritic cells (DC) can enhance antigen presentation and activate cytotoxic T-cells against poorly immunogenic tumors. However, cancer immunotherapy trials also suggest that αCD40 is only moderately effective in patients, falling s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Singh, Akansha, Ranjan, Ashish
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050348/ https://www.ncbi.nlm.nih.gov/pubmed/37006295 http://dx.doi.org/10.3389/fimmu.2023.1141712

Ejemplares similares

TLR–CD40 Cross-Talk in Anti-Leishmanial Immune Response
por: Chandel, Himanshu Singh, et al.
Publicado: (2014)

Adrenergic Signaling in Circadian Control of Immunity
por: Leach, Sarah, et al.
Publicado: (2020)

Signaling via a CD28/CD40 chimeric costimulatory antigen receptor (CoStAR™), targeting folate receptor alpha, enhances T cell activity and augments tumor reactivity of tumor infiltrating lymphocytes
por: Kalaitsidou, Milena, et al.
Publicado: (2023)

The impact of β-adrenergic signaling on radioresistance and anti-tumor immunity
por: Bucsek, Mark, et al.
Publicado: (2015)

Alpha2B-Adrenergic Receptor Regulates Neutrophil Recruitment in MSU-Induced Peritoneal Inflammation
por: Duan, Lihua, et al.
Publicado: (2019)

Genetic Adjuvantation of Recombinant MVA with CD40L Potentiates CD8 T Cell Mediated Immunity
por: Lauterbach, Henning, et al.
Publicado: (2013)

The Mannose Receptor in Regulation of Helminth-Mediated Host Immunity
por: van Die, Irma, et al.
Publicado: (2017)

Systemic β-Adrenergic Receptor Activation Augments the ex vivo Expansion and Anti-Tumor Activity of Vγ9Vδ2 T-Cells
por: Baker, Forrest L., et al.
Publicado: (2020)

The CD40 agonist HERA-CD40L results in enhanced activation of antigen presenting cells, promoting an anti-tumor effect alone and in combination with radiotherapy
por: Frankish, Jamie, et al.
Publicado: (2023)

Role of adrenergic receptors in shock
por: Geevarghese, Mathew, et al.
Publicado: (2023)

CD40-Mediated Maintenance of Immune Homeostasis in the Adipose Tissue Microenvironment
por: Yi, Zuoan, et al.
Publicado: (2014)

G protein-coupled receptor 183 mediates the sensitization of Burkitt lymphoma tumors to CD47 immune checkpoint blockade by anti-CD20/PI3Kδi dual therapy
por: Ribeiro, Marcelo Lima, et al.
Publicado: (2023)

Regulation of C-Type Lectin Receptor-Mediated Antifungal Immunity
por: Tang, Juan, et al.
Publicado: (2018)

Adrenergic Signaling: A Targetable Checkpoint Limiting Development of the Antitumor Immune Response
por: Qiao, Guanxi, et al.
Publicado: (2018)

Toll-Like Receptor Signaling and Its Role in Cell-Mediated Immunity
por: Duan, Tianhao, et al.
Publicado: (2022)

The Cholinergic and Adrenergic Autocrine Signaling Pathway Mediates Immunomodulation in Oyster Crassostrea gigas
por: Liu, Zhaoqun, et al.
Publicado: (2018)

PKC-theta-mediated signal delivery from the TCR/CD28 surface receptors
por: Isakov, Noah, et al.
Publicado: (2012)

Anti-CD40 Antibody Fused to CD40 Ligand Is a Superagonist Platform for Adjuvant Intrinsic DC-Targeting Vaccines
por: Ceglia, Valentina, et al.
Publicado: (2022)

Anti-tumor memory CD4 and CD8 T-cells quantified by bulk T-cell receptor (TCR) clonal analysis
por: Gao, Yanhua, et al.
Publicado: (2023)

Wnt Signaling Cascade in Dendritic Cells and Regulation of Anti-tumor Immunity
por: Suryawanshi, Amol, et al.
Publicado: (2020)

NOTCH Signaling in T-Cell-Mediated Anti-Tumor Immunity and T-Cell-Based Immunotherapies
por: Kelliher, Michelle A., et al.
Publicado: (2018)

Immunometabolic Regulations Mediated by Coinhibitory Receptors and Their Impact on T Cell Immune Responses
por: Patsoukis, Nikolaos, et al.
Publicado: (2017)

Agonistic Autoantibodies to the β2-Adrenergic Receptor Involved in the Pathogenesis of Open-Angle Glaucoma
por: Jünemann, Anselm, et al.
Publicado: (2018)

Autoantibodies Activating the β2-Adrenergic Receptor Characterize Patients With Primary and Secondary Glaucoma
por: Hohberger, Bettina, et al.
Publicado: (2019)

The α(1)-adrenergic receptors: diversity of signaling networks and regulation
por: Cotecchia, Susanna
Publicado: (2010)

Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma
por: Wolter, Jennifer K, et al.
Publicado: (2013)

CD40 Activity on Mesenchymal Cells Negatively Regulates OX40L to Maintain Bone Marrow Immune Homeostasis Under Stress Conditions
por: Bassani, Barbara, et al.
Publicado: (2021)

The Aryl Hydrocarbon Receptor and Tumor Immunity
por: Xue, Ping, et al.
Publicado: (2018)

Platelets as Key Factors in Inflammation: Focus on CD40L/CD40
por: Cognasse, Fabrice, et al.
Publicado: (2022)

Regulation of the PKCθ-NF-κB Axis in T Lymphocytes by the Tumor Necrosis Factor Receptor Family Member OX40
por: So, Takanori, et al.
Publicado: (2012)

Regulation of Interleukin-6 Receptor Signaling by TNF Receptor-Associated Factor 2 and 5 During Differentiation of Inflammatory CD4(+) T Cells
por: Nagashima, Hiroyuki, et al.
Publicado: (2018)

miR-128 Regulates Tumor Cell CD47 Expression and Promotes Anti-tumor Immunity in Pancreatic Cancer
por: Xi, Qing, et al.
Publicado: (2020)

4-1BB Signaling Boosts the Anti-Tumor Activity of CD28-Incorporated 2(nd) Generation Chimeric Antigen Receptor-Modified T Cells
por: Dai, Qiang, et al.
Publicado: (2020)

CD40-Mediated Activation of the NF-κB2 Pathway
por: Hostager, Bruce S., et al.
Publicado: (2013)

The Contribution of CD40/CD40L Axis in Inflammatory Bowel Disease: An Update
por: Senhaji, Nezha, et al.
Publicado: (2015)

The CD40–CD40L Dyad in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis
por: Aarts, Suzanne A. B. M., et al.
Publicado: (2017)

CD28 and chemokine receptors: Signalling amplifiers at the immunological synapse
por: Molon, Barbara, et al.
Publicado: (2022)

Adrenergic Signaling at the Interface of Allergic Asthma and Viral Infections
por: Ağaç, Didem, et al.
Publicado: (2018)

The CD28-Transmembrane Domain Mediates Chimeric Antigen Receptor Heterodimerization With CD28
por: Muller, Yannick D., et al.
Publicado: (2021)

Pentraxins and Fc Receptor-Mediated Immune Responses
por: Lu, Jinghua, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_cg3pq7rmqqa2c7bugt58rg6avg