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Iron response elements (IREs)-mRNA of Alzheimer's amyloid precursor protein binding to iron regulatory protein (IRP1): a combined molecular docking and spectroscopic approach

The interaction between the stem-loop structure of the Alzheimer's amyloid precursor protein IRE mRNA and iron regulatory protein was examined by employing molecular docking and multi-spectroscopic techniques. A detailed molecular docking analysis of APP IRE mRNA∙IRP1 reveals that 11 residues a...

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Detalles Bibliográficos
Autores principales:	Khan, Mateen A., Mohammad, Taj, Malik, Ajamaluddin, Hassan, Md. Imtaiyaz, Domashevskiy, Artem V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050399/ https://www.ncbi.nlm.nih.gov/pubmed/36977734 http://dx.doi.org/10.1038/s41598-023-32073-x

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