Cargando…
Transcriptomics of CD29(+)/CD44(+) cells isolated from hPSC retinal organoids reveals a single cell population with retinal progenitor and Müller glia characteristics
Müller glia play very important and diverse roles in retinal homeostasis and disease. Although much is known of the physiological and morphological properties of mammalian Müller glia, there is still the need to further understand the profile of these cells during human retinal development. Using hu...
Autores principales: | Eastlake, Karen, Luis, Joshua, Wang, Weixin, Lamb, William, Khaw, Peng T., Limb, G. Astrid |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050419/ https://www.ncbi.nlm.nih.gov/pubmed/36977817 http://dx.doi.org/10.1038/s41598-023-32058-w |
Ejemplares similares
-
Phenotypic and Functional Characterization of Müller Glia Isolated from Induced Pluripotent Stem Cell‐Derived Retinal Organoids: Improvement of Retinal Ganglion Cell Function upon Transplantation
por: Eastlake, Karen, et al.
Publicado: (2019) -
Comparative proteomic analysis of normal and gliotic PVR retina and contribution of Müller glia to this profile
por: Eastlake, Karen, et al.
Publicado: (2018) -
Single-Cell Transcriptomic Comparison of Human Fetal Retina, hPSC-Derived Retinal Organoids, and Long-Term Retinal Cultures
por: Sridhar, Akshayalakshmi, et al.
Publicado: (2020) -
Allogeneic Transplantation of Müller-Derived Retinal Ganglion Cells Improves Retinal Function in a Feline Model of Ganglion Cell Depletion
por: Becker, Silke, et al.
Publicado: (2016) -
Müller glia as an important source of cytokines and inflammatory factors present in the gliotic retina during proliferative vitreoretinopathy
por: Eastlake, K., et al.
Publicado: (2015)