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Global research on the crosstalk between intestinal microbiome and colorectal cancer: A visualization analysis

BACKGROUND: Increasing evidence has shown that the intestinal microbiome (IM) is highly linked to colorectal cancer (CRC). To investigate scientific output, identify highly cited papers, and explore research hotspots and trends in the field of IM/CRC, we conducted a bibliometric and visualized analy...

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Autores principales: Yang, Shanshan, Hao, Shaodong, Ye, Hui, Zhang, Xuezhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050574/
https://www.ncbi.nlm.nih.gov/pubmed/37009513
http://dx.doi.org/10.3389/fcimb.2023.1083987
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author Yang, Shanshan
Hao, Shaodong
Ye, Hui
Zhang, Xuezhi
author_facet Yang, Shanshan
Hao, Shaodong
Ye, Hui
Zhang, Xuezhi
author_sort Yang, Shanshan
collection PubMed
description BACKGROUND: Increasing evidence has shown that the intestinal microbiome (IM) is highly linked to colorectal cancer (CRC). To investigate scientific output, identify highly cited papers, and explore research hotspots and trends in the field of IM/CRC, we conducted a bibliometric and visualized analysis. METHODS: A bibliographic search regarding IM/CRC research (2012-2021) was implemented on October 17, 2022. The terms attached to IM and CRC were searched for in the titles (TI), abstracts (AB), and author keywords (AK). The main information was extracted from the Web of Science Core Collection (WoSCC). Biblioshiny from R packages and VOSviewer were used for data visualization. RESULTS: A total of 1725 papers related to IM/CRC were retrieved. Publications on IM/CRC have grown rapidly from 2012 to 2021. China and the United States were in the leading position for publications in this field and made the most significant contributions to IM/CRC research. Shanghai Jiao Tong University and Harvard University were the most productive institutions. The high-yield authors were Yu Jun and Fang Jing Yuan. The International Journal of Molecular Sciences published the most papers, whereas Gut had the most citations. Historical citation analysis showed the evolution of IM/CRC research. Current status and hotspots were highlighted using keyword cluster analysis. The hot topics include the effect of IM on tumorigenesis, the effect of IM on CRC treatment, the role of IM in CRC screening, the mechanisms of IM involvement in CRC, and IM modulation for CRC management. Some topics, such as chemotherapy, immunotherapy, Fusobacterium nucleatum and short-chain fatty acids could be the focus of IM/CRC research in the coming years. CONCLUSION: This research evaluated the global scientific output of IM/CRC research and its quantitative features, identified some significant papers, and gathered information on the status and trends of IM/CRC research, which may shape future paths for academics and practitioners.
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spelling pubmed-100505742023-03-30 Global research on the crosstalk between intestinal microbiome and colorectal cancer: A visualization analysis Yang, Shanshan Hao, Shaodong Ye, Hui Zhang, Xuezhi Front Cell Infect Microbiol Cellular and Infection Microbiology BACKGROUND: Increasing evidence has shown that the intestinal microbiome (IM) is highly linked to colorectal cancer (CRC). To investigate scientific output, identify highly cited papers, and explore research hotspots and trends in the field of IM/CRC, we conducted a bibliometric and visualized analysis. METHODS: A bibliographic search regarding IM/CRC research (2012-2021) was implemented on October 17, 2022. The terms attached to IM and CRC were searched for in the titles (TI), abstracts (AB), and author keywords (AK). The main information was extracted from the Web of Science Core Collection (WoSCC). Biblioshiny from R packages and VOSviewer were used for data visualization. RESULTS: A total of 1725 papers related to IM/CRC were retrieved. Publications on IM/CRC have grown rapidly from 2012 to 2021. China and the United States were in the leading position for publications in this field and made the most significant contributions to IM/CRC research. Shanghai Jiao Tong University and Harvard University were the most productive institutions. The high-yield authors were Yu Jun and Fang Jing Yuan. The International Journal of Molecular Sciences published the most papers, whereas Gut had the most citations. Historical citation analysis showed the evolution of IM/CRC research. Current status and hotspots were highlighted using keyword cluster analysis. The hot topics include the effect of IM on tumorigenesis, the effect of IM on CRC treatment, the role of IM in CRC screening, the mechanisms of IM involvement in CRC, and IM modulation for CRC management. Some topics, such as chemotherapy, immunotherapy, Fusobacterium nucleatum and short-chain fatty acids could be the focus of IM/CRC research in the coming years. CONCLUSION: This research evaluated the global scientific output of IM/CRC research and its quantitative features, identified some significant papers, and gathered information on the status and trends of IM/CRC research, which may shape future paths for academics and practitioners. Frontiers Media S.A. 2023-03-15 /pmc/articles/PMC10050574/ /pubmed/37009513 http://dx.doi.org/10.3389/fcimb.2023.1083987 Text en Copyright © 2023 Yang, Hao, Ye and Zhang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cellular and Infection Microbiology
Yang, Shanshan
Hao, Shaodong
Ye, Hui
Zhang, Xuezhi
Global research on the crosstalk between intestinal microbiome and colorectal cancer: A visualization analysis
title Global research on the crosstalk between intestinal microbiome and colorectal cancer: A visualization analysis
title_full Global research on the crosstalk between intestinal microbiome and colorectal cancer: A visualization analysis
title_fullStr Global research on the crosstalk between intestinal microbiome and colorectal cancer: A visualization analysis
title_full_unstemmed Global research on the crosstalk between intestinal microbiome and colorectal cancer: A visualization analysis
title_short Global research on the crosstalk between intestinal microbiome and colorectal cancer: A visualization analysis
title_sort global research on the crosstalk between intestinal microbiome and colorectal cancer: a visualization analysis
topic Cellular and Infection Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050574/
https://www.ncbi.nlm.nih.gov/pubmed/37009513
http://dx.doi.org/10.3389/fcimb.2023.1083987
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