Oncolytic viruses-modulated immunogenic cell death, apoptosis and autophagy linking to virotherapy and cancer immune response

Recent reports have revealed that oncolytic viruses (OVs) play a significant role in cancer therapy. The infection of OVs such as oncolytic vaccinia virus (OVV), vesicular stomatitis virus (VSV), parvovirus, mammalian reovirus (MRV), human adenovirus, Newcastle disease virus (NDV), herpes simplex vi...

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Autores principales: Wu, Yi-Ying, Sun, Te-Kai, Chen, Ming-Shan, Munir, Muhammad, Liu, Hung-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050605/
https://www.ncbi.nlm.nih.gov/pubmed/37009515
http://dx.doi.org/10.3389/fcimb.2023.1142172
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author Wu, Yi-Ying
Sun, Te-Kai
Chen, Ming-Shan
Munir, Muhammad
Liu, Hung-Jen
author_facet Wu, Yi-Ying
Sun, Te-Kai
Chen, Ming-Shan
Munir, Muhammad
Liu, Hung-Jen
author_sort Wu, Yi-Ying
collection PubMed
description Recent reports have revealed that oncolytic viruses (OVs) play a significant role in cancer therapy. The infection of OVs such as oncolytic vaccinia virus (OVV), vesicular stomatitis virus (VSV), parvovirus, mammalian reovirus (MRV), human adenovirus, Newcastle disease virus (NDV), herpes simplex virus (HSV), avian reovirus (ARV), Orf virus (ORFV), inactivated Sendai virus (ISV), enterovirus, and coxsackievirus offer unique opportunities in immunotherapy through diverse and dynamic pathways. This mini-review focuses on the mechanisms of OVs-mediated virotherapy and their effects on immunogenic cell death (ICD), apoptosis, autophagy and regulation of the immune system.
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spelling pubmed-100506052023-03-30 Oncolytic viruses-modulated immunogenic cell death, apoptosis and autophagy linking to virotherapy and cancer immune response Wu, Yi-Ying Sun, Te-Kai Chen, Ming-Shan Munir, Muhammad Liu, Hung-Jen Front Cell Infect Microbiol Cellular and Infection Microbiology Recent reports have revealed that oncolytic viruses (OVs) play a significant role in cancer therapy. The infection of OVs such as oncolytic vaccinia virus (OVV), vesicular stomatitis virus (VSV), parvovirus, mammalian reovirus (MRV), human adenovirus, Newcastle disease virus (NDV), herpes simplex virus (HSV), avian reovirus (ARV), Orf virus (ORFV), inactivated Sendai virus (ISV), enterovirus, and coxsackievirus offer unique opportunities in immunotherapy through diverse and dynamic pathways. This mini-review focuses on the mechanisms of OVs-mediated virotherapy and their effects on immunogenic cell death (ICD), apoptosis, autophagy and regulation of the immune system. Frontiers Media S.A. 2023-03-15 /pmc/articles/PMC10050605/ /pubmed/37009515 http://dx.doi.org/10.3389/fcimb.2023.1142172 Text en Copyright © 2023 Wu, Sun, Chen, Munir and Liu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cellular and Infection Microbiology
Wu, Yi-Ying
Sun, Te-Kai
Chen, Ming-Shan
Munir, Muhammad
Liu, Hung-Jen
Oncolytic viruses-modulated immunogenic cell death, apoptosis and autophagy linking to virotherapy and cancer immune response
title Oncolytic viruses-modulated immunogenic cell death, apoptosis and autophagy linking to virotherapy and cancer immune response
title_full Oncolytic viruses-modulated immunogenic cell death, apoptosis and autophagy linking to virotherapy and cancer immune response
title_fullStr Oncolytic viruses-modulated immunogenic cell death, apoptosis and autophagy linking to virotherapy and cancer immune response
title_full_unstemmed Oncolytic viruses-modulated immunogenic cell death, apoptosis and autophagy linking to virotherapy and cancer immune response
title_short Oncolytic viruses-modulated immunogenic cell death, apoptosis and autophagy linking to virotherapy and cancer immune response
title_sort oncolytic viruses-modulated immunogenic cell death, apoptosis and autophagy linking to virotherapy and cancer immune response
topic Cellular and Infection Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050605/
https://www.ncbi.nlm.nih.gov/pubmed/37009515
http://dx.doi.org/10.3389/fcimb.2023.1142172
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