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Survival differences of low‐grade versus high‐grade head and neck pleomorphic dermal sarcomas and a review of a scalp case

OBJECTIVE: To examine survival by tumor grade of pleomorphic dermal sarcomas (PDS) of the head and neck (H&N) and review a scalp PDS case. METHODS: Patients in the Surveillance, Epidemiology, and End Results (SEER) database were included from 1980 to 2016 based on a diagnosis of H&N PDS. Sur...

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Autores principales: Janz, Tyler A., Long, Barry D., Joshi, Rohan R., Coblens, Orly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050964/
https://www.ncbi.nlm.nih.gov/pubmed/37006751
http://dx.doi.org/10.1002/wjo2.64
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author Janz, Tyler A.
Long, Barry D.
Joshi, Rohan R.
Coblens, Orly M.
author_facet Janz, Tyler A.
Long, Barry D.
Joshi, Rohan R.
Coblens, Orly M.
author_sort Janz, Tyler A.
collection PubMed
description OBJECTIVE: To examine survival by tumor grade of pleomorphic dermal sarcomas (PDS) of the head and neck (H&N) and review a scalp PDS case. METHODS: Patients in the Surveillance, Epidemiology, and End Results (SEER) database were included from 1980 to 2016 based on a diagnosis of H&N PDS. Survival estimates were performed using Kaplan–Meier analysis. Additionally, a case of a grade III H&N PDS is presented. RESULTS: Two hundred‐seventy cases of PDS were identified. The mean age at diagnosis was 75.1 years (SD: 13.5). Two hundred‐thirty‐four (86.7%) patients were male. Eighty‐seven percent of patients received surgery as a part of their care. The 5‐year overall survival rates for grades I, II, III, and IV PDSs were 69%, 60%, 50%, and 42%, respectively (P = 0.03). CONCLUSIONS: H&N PDS occurs most commonly in older‐age males. Surgical management is frequently a part of H&N PDS care. Survival rates significantly decline based on tumor grade.
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spelling pubmed-100509642023-03-30 Survival differences of low‐grade versus high‐grade head and neck pleomorphic dermal sarcomas and a review of a scalp case Janz, Tyler A. Long, Barry D. Joshi, Rohan R. Coblens, Orly M. World J Otorhinolaryngol Head Neck Surg Research Papers OBJECTIVE: To examine survival by tumor grade of pleomorphic dermal sarcomas (PDS) of the head and neck (H&N) and review a scalp PDS case. METHODS: Patients in the Surveillance, Epidemiology, and End Results (SEER) database were included from 1980 to 2016 based on a diagnosis of H&N PDS. Survival estimates were performed using Kaplan–Meier analysis. Additionally, a case of a grade III H&N PDS is presented. RESULTS: Two hundred‐seventy cases of PDS were identified. The mean age at diagnosis was 75.1 years (SD: 13.5). Two hundred‐thirty‐four (86.7%) patients were male. Eighty‐seven percent of patients received surgery as a part of their care. The 5‐year overall survival rates for grades I, II, III, and IV PDSs were 69%, 60%, 50%, and 42%, respectively (P = 0.03). CONCLUSIONS: H&N PDS occurs most commonly in older‐age males. Surgical management is frequently a part of H&N PDS care. Survival rates significantly decline based on tumor grade. John Wiley and Sons Inc. 2022-04-18 /pmc/articles/PMC10050964/ /pubmed/37006751 http://dx.doi.org/10.1002/wjo2.64 Text en © 2022 The Authors. World Journal of Otorhinolaryngology ‐ Head and Neck Surgery published by John Wiley & Sons Ltd on behalf of Chinese Medical Association. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Research Papers
Janz, Tyler A.
Long, Barry D.
Joshi, Rohan R.
Coblens, Orly M.
Survival differences of low‐grade versus high‐grade head and neck pleomorphic dermal sarcomas and a review of a scalp case
title Survival differences of low‐grade versus high‐grade head and neck pleomorphic dermal sarcomas and a review of a scalp case
title_full Survival differences of low‐grade versus high‐grade head and neck pleomorphic dermal sarcomas and a review of a scalp case
title_fullStr Survival differences of low‐grade versus high‐grade head and neck pleomorphic dermal sarcomas and a review of a scalp case
title_full_unstemmed Survival differences of low‐grade versus high‐grade head and neck pleomorphic dermal sarcomas and a review of a scalp case
title_short Survival differences of low‐grade versus high‐grade head and neck pleomorphic dermal sarcomas and a review of a scalp case
title_sort survival differences of low‐grade versus high‐grade head and neck pleomorphic dermal sarcomas and a review of a scalp case
topic Research Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050964/
https://www.ncbi.nlm.nih.gov/pubmed/37006751
http://dx.doi.org/10.1002/wjo2.64
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