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Survival differences of low‐grade versus high‐grade head and neck pleomorphic dermal sarcomas and a review of a scalp case
OBJECTIVE: To examine survival by tumor grade of pleomorphic dermal sarcomas (PDS) of the head and neck (H&N) and review a scalp PDS case. METHODS: Patients in the Surveillance, Epidemiology, and End Results (SEER) database were included from 1980 to 2016 based on a diagnosis of H&N PDS. Sur...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050964/ https://www.ncbi.nlm.nih.gov/pubmed/37006751 http://dx.doi.org/10.1002/wjo2.64 |
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author | Janz, Tyler A. Long, Barry D. Joshi, Rohan R. Coblens, Orly M. |
author_facet | Janz, Tyler A. Long, Barry D. Joshi, Rohan R. Coblens, Orly M. |
author_sort | Janz, Tyler A. |
collection | PubMed |
description | OBJECTIVE: To examine survival by tumor grade of pleomorphic dermal sarcomas (PDS) of the head and neck (H&N) and review a scalp PDS case. METHODS: Patients in the Surveillance, Epidemiology, and End Results (SEER) database were included from 1980 to 2016 based on a diagnosis of H&N PDS. Survival estimates were performed using Kaplan–Meier analysis. Additionally, a case of a grade III H&N PDS is presented. RESULTS: Two hundred‐seventy cases of PDS were identified. The mean age at diagnosis was 75.1 years (SD: 13.5). Two hundred‐thirty‐four (86.7%) patients were male. Eighty‐seven percent of patients received surgery as a part of their care. The 5‐year overall survival rates for grades I, II, III, and IV PDSs were 69%, 60%, 50%, and 42%, respectively (P = 0.03). CONCLUSIONS: H&N PDS occurs most commonly in older‐age males. Surgical management is frequently a part of H&N PDS care. Survival rates significantly decline based on tumor grade. |
format | Online Article Text |
id | pubmed-10050964 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100509642023-03-30 Survival differences of low‐grade versus high‐grade head and neck pleomorphic dermal sarcomas and a review of a scalp case Janz, Tyler A. Long, Barry D. Joshi, Rohan R. Coblens, Orly M. World J Otorhinolaryngol Head Neck Surg Research Papers OBJECTIVE: To examine survival by tumor grade of pleomorphic dermal sarcomas (PDS) of the head and neck (H&N) and review a scalp PDS case. METHODS: Patients in the Surveillance, Epidemiology, and End Results (SEER) database were included from 1980 to 2016 based on a diagnosis of H&N PDS. Survival estimates were performed using Kaplan–Meier analysis. Additionally, a case of a grade III H&N PDS is presented. RESULTS: Two hundred‐seventy cases of PDS were identified. The mean age at diagnosis was 75.1 years (SD: 13.5). Two hundred‐thirty‐four (86.7%) patients were male. Eighty‐seven percent of patients received surgery as a part of their care. The 5‐year overall survival rates for grades I, II, III, and IV PDSs were 69%, 60%, 50%, and 42%, respectively (P = 0.03). CONCLUSIONS: H&N PDS occurs most commonly in older‐age males. Surgical management is frequently a part of H&N PDS care. Survival rates significantly decline based on tumor grade. John Wiley and Sons Inc. 2022-04-18 /pmc/articles/PMC10050964/ /pubmed/37006751 http://dx.doi.org/10.1002/wjo2.64 Text en © 2022 The Authors. World Journal of Otorhinolaryngology ‐ Head and Neck Surgery published by John Wiley & Sons Ltd on behalf of Chinese Medical Association. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Research Papers Janz, Tyler A. Long, Barry D. Joshi, Rohan R. Coblens, Orly M. Survival differences of low‐grade versus high‐grade head and neck pleomorphic dermal sarcomas and a review of a scalp case |
title | Survival differences of low‐grade versus high‐grade head and neck pleomorphic dermal sarcomas and a review of a scalp case |
title_full | Survival differences of low‐grade versus high‐grade head and neck pleomorphic dermal sarcomas and a review of a scalp case |
title_fullStr | Survival differences of low‐grade versus high‐grade head and neck pleomorphic dermal sarcomas and a review of a scalp case |
title_full_unstemmed | Survival differences of low‐grade versus high‐grade head and neck pleomorphic dermal sarcomas and a review of a scalp case |
title_short | Survival differences of low‐grade versus high‐grade head and neck pleomorphic dermal sarcomas and a review of a scalp case |
title_sort | survival differences of low‐grade versus high‐grade head and neck pleomorphic dermal sarcomas and a review of a scalp case |
topic | Research Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10050964/ https://www.ncbi.nlm.nih.gov/pubmed/37006751 http://dx.doi.org/10.1002/wjo2.64 |
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