Transcriptional Regulation of Liver-Type OATP1B3 (Lt-OATP1B3) and Cancer-Type OATP1B3 (Ct-OATP1B3) Studied in Hepatocyte-Derived and Colon Cancer-Derived Cell Lines

Due to alternative splicing, the SLCO1B3 gene encodes two protein variants; the hepatic uptake transporter liver-type OATP1B3 (Lt-OATP1B3) and the cancer-type OATP1B3 (Ct-OATP1B3) expressed in several cancerous tissues. There is limited information about the cell type-specific transcriptional regula...

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Detalles Bibliográficos
Autores principales: Haberkorn, Bastian, Löwen, Dennis, Meier, Lukas, Fromm, Martin F., König, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051083/
https://www.ncbi.nlm.nih.gov/pubmed/36986600
http://dx.doi.org/10.3390/pharmaceutics15030738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051083/
https://www.ncbi.nlm.nih.gov/pubmed/36986600
http://dx.doi.org/10.3390/pharmaceutics15030738

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