Pregnancy Is Associated with Impaired Transcription of Human Endogenous Retroviruses and of TRIM28 and SETDB1, Particularly in Mothers Affected by Multiple Sclerosis

Accumulating evidence highlights the pathogenetic role of human endogenous retroviruses (HERVs) in eliciting and maintaining multiple sclerosis (MS). Epigenetic mechanisms, such as those regulated by TRIM 28 and SETDB1, are implicated in HERV activation and in neuroinflammatory disorders, including...

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Detalles Bibliográficos
Autores principales: Tovo, Pier-Angelo, Marozio, Luca, Abbona, Giancarlo, Calvi, Cristina, Frezet, Federica, Gambarino, Stefano, Dini, Maddalena, Benedetto, Chiara, Galliano, Ilaria, Bergallo, Massimiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10051116/
https://www.ncbi.nlm.nih.gov/pubmed/36992419
http://dx.doi.org/10.3390/v15030710

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